The Use of Androgen Deprivation in Conjunction with Radiation in Localized Prostate Cancer
نویسندگان
چکیده
Background: In prostate carcinoma, there is controversy about optimal use of hormonal therapy with external beam radiotherapy: who will benefit, for how long, neo-adjuvant versus concurrent versus adjuvant. Patients and Methods: Evidence from randomized studies in the light of recent published articles and updates were reviewed in order to address these issues. Results and Conclusions: From this review it was concluded that the benefit of long-term hormonal therapy in combination with conventional-dose radiotherapy (<74 Gy) in high-risk prostate cancer is evident. For the intermediate risk, the evidence is still weak and studies are awaited to clarify this matter.
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